Proteomics & Mass Spectrometry:
Post-Translational Modification (PTM) enrichment (e.g., phospho, glyco, ubiquitin), affinity pull-downs and fractionation, SP3/PAC and bead clean-up workflows, and high purity MALDI/ESI MS sample preparation.
Genomics & Gene Expression:
DNA/RNA purification, library screening (e.g., ADMET workflows), transfection and RNAi/siRNA workflows, as well as total and plant DNA/RNA purification solutions.
Cell and Assay Applications:
High-throughput Extracellular Vesicle (EV) cell isolation (positive/negative selection), immuno- and receptor assays, affinity screening, and multiplexed bead assays.
Key Benefits
· High yield and minimal loss chemistry with complex and low abundance samples.
· Open platform allows integration with other automation processes
· Technology allows sample volume scaling up to milliLitres.
· Improves efficiency by disconnecting magnetic bead processing from liquid handling.
· Compatibility with established magnetic bead chemistry.
· Efficient removal of salts, detergents and digestion reagents for downstream analyses (eg mass spec and nucleic acid amplification).
· The “move beads” approach minimizes carry over vs moving liquids (ie no adsorption of unwanted artefacts).
· High throughput, reproducibility and reduced hands-on time.
